Abstract: The KFC Fast-growing Chicken Event has aroused public attention and doubts on product safety status of KFC and food safety environment in China. When facing this crisis, KFC adopts the strategy of “Denial-Remedy-Explanatory Advertising”. With an analysis of related contents in Sina Micro-blogs, this paper mainly studies whether public perception and attitude towards the event will change with public relations advertising on food safety. The research suggests that the advertisements that are focused on KFC food safetycan enhance public understanding of its food safety, foster a positive public attitude, reduce people’s risk perception and direct them to attribute the event to external reasons. However, the advertisements have not fundamentally changed public attitude to food safety problems of KFC.